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Acetaminophen, Dextromethorphan, and Phenylephrine Oral Drops e Fluvoxamine ER Capsules

Definición de la interacción Acetaminophen, Dextromethorphan, and Phenylephrine Oral Drops e Fluvoxamine ER Capsules y posibilidad de tomarlos juntos.

Resultado de la verificación:

Acetaminophen, Dextromethorphan, and Phenylephrine Oral Drops <> Fluvoxamine ER Capsules

Relevancia: 10.04.2023 Examinador: P.M. Shkutko, M.D., in

En la base de datos de directorios oficiales utilizados para crear el servicio, se encontró una interacción confirmada estadísticamente mediante los resultados de la investigación, que puede conducir a consecuencias negativas para la salud del paciente o aumentar el efecto positivo de cada medicamento. Se requiere una consulta médica para resolver el problema de la administración simultanea de los medicamentos.

Consumidor:

Hable con su médico antes de usar dextromethorphan junto con fluvoxamina. La combinación de estos medicamentos puede aumentar el riesgo de una rara pero grave enfermedad llamada el síndrome de la serotonina, que puede incluir síntomas tales como confusión, alucinaciones, convulsiones, cambios bruscos en la presión arterial, aumento del ritmo del corazón, fiebre, sudoración excesiva, escalofríos o temblores, visión borrosa, espasmos musculares o rigidez, temblor, incoordinación, estómago calambres, náuseas, vómitos, y diarrea. Los casos severos pueden resultar en coma e incluso la muerte. Usted debe contactar a su médico inmediatamente si usted experimenta estos síntomas mientras esté tomando los medicamentos. Es importante decirle a su médico acerca de todas las medicinas que usted use, incluyendo vitaminas y hierbas. No deje de tomar ningún medicamento sin hablar primero con su médico.

Profesional:

VIGILAR de CERCA: el uso Concomitante de agentes con actividad serotoninérgica como de la recaptación de serotonina, inhibidores de la monoaminooxidasa, antidepresivos tricíclicos, los receptores 5-HT1 agonistas, alcaloides del cornezuelo de centeno, de litio, la hierba de San Juan, phenylpiperidine opioides, dextromethorphan, y el triptófano puede potenciar el riesgo de síndrome de serotonina, que es una rara pero grave y potencialmente fatal condición se cree que el resultado de la hiperestimulación de tronco cerebral de 5-HT1A y 2A receptores. Los síntomas del síndrome serotoninérgico pueden incluir cambios en el estado mental, tales como irritabilidad, alteración de la conciencia, confusión, alucinación, y coma; la disfunción autonómica tales como taquicardia, hipertermia, diaforesis, temblor, la labilidad de la presión arterial, y midriasis; las anormalidades neuromusculares tales como hiperreflexia, mioclonías, temblor, rigidez, y ataxia; y síntomas gastrointestinales tales como calambres abdominales, náuseas, vómitos, y diarrea.

ADMINISTRACIÓN: En general, el uso concomitante de múltiples agentes serotoninérgicos debe ser evitado si es posible, o de lo contrario, se acercó con precaución si el beneficio potencial se considera superan los riesgos. Algunos fabricantes consideran el uso concomitante de dextrometorfano y selectivo de la recaptación de serotonina inhibidores de la contraindicado. Si el tratamiento concomitante es necesario, los pacientes deben ser estrechamente monitorizados para detectar síntomas del síndrome de la serotonina durante el tratamiento. En Particular se recomienda precaución al aumentar la dosis de estos agentes. El potencial de riesgo para el síndrome de la serotonina debe considerarse aún cuando la administración de agentes serotoninérgicos de forma secuencial, ya que algunos agentes pueden demostrar una prolongada vida media de eliminación (por ejemplo, fluoxetina). Si el síndrome de la serotonina se desarrolla o se sospecha que durante el curso de la terapia, todos los agentes serotoninérgicos debe suspender inmediatamente el tratamiento y la atención de apoyo prestados como sea necesario. Moderadamente enfermo pacientes también pueden beneficiarse de la administración de un antagonista de la serotonina (por ejemplo, ciproheptadina, clorpromazina). Los casos graves deben ser manejados bajo consulta con un toxicólogo y puede requerir sedación, parálisis neuromuscular, la intubación y la ventilación mecánica, además de otras medidas.

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Acetaminophen, Dextromethorphan, and Phenylephrine Oral Drops

Nombre genérico: acetaminophen / dextromethorphan / phenylephrine

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Sinónimos: Acetaminophen, dextromethorphan, and phenylephrine

¿Qué es Acetaminophen, Dextromethorphan, and Phenylephrine Oral Drops?